In prostate cancer cells, Ox-LOL-induced overexpression of LOX-1 resulted in epithelial-mesenchymal transformation and promoted cancer cell invasion and migration by reducing the expression of epithelial markers (such as cadherin and platelet globin) and increasing the expression of mesenchymal markers (like vimentin, N-cadherin, snails, slugs, MMP-2, and MMP-9) (165). This evidence concerns the gene MMP9 and cancer.