For example, Quercetin (3,3,4,5,7‐pentahydroxyflavone, QE) improved liver fibrosis induced by BDL and CCl4 through attenuating HSCs activation and reducing autophagy, which regulates crosstalk between the TGF‐β1/Smads and PI3K/Akt pathways.90 The gene discussed is TGFB1; the disease is Hepatic fibrosis.