METTL14 and colorectal carcinoma: stearoyl-CoA desaturase 1 (SCD1) is also a downstream target gene of METTL14-mediated m6 A modification, which can reduce the level of SCD1 mRNA through m6A modification of SCD1 mRNA in a YTHDF 2-dependent manner, and then inhibit the tumorigenic process of CRC through the SCD1-mediated Wnt/β-catenin signaling pathway [155].