METTL3 and posterior cortical atrophy: METTL3 is a poor prognostic factor for overall and disease-free survival in PCa.METTL3 can also enhance MYC (c-myc) expression to promote PCa cell proliferation, invasion, and migration by increasing the level of m6 A of MYC mRNA transcripts, which is a poor prognostic factor for overall and disease-free survival in patients with PCa [131].