In regard with obesity, breastmilk seems to have a protective effect, because of a reduced percentage of proteins and the presence of leptin, insulin, GLP-1 (Glucagon-like peptide-1), gastrointestinal peptide, and adiponectin, directly involved in the mechanisms of metabolic regulation and hunger/satiety balance [2]. The gene discussed is GCG; the disease is obesity due to melanocortin 4 receptor deficiency.