The 16-gene TREM1 myeloid signature score was low among eczema and psoriasis patients despite the loss of epithelial barrier function associated with those skin conditions, whereas BIT associated TREM1 myeloid signature was higher in cancers that are more closely associated with inflammation (colorectal, ovarian and thyroid cancers) (Fig. 5g). The gene discussed is SIRPA; the disease is thyroid cancer.