ORMDL3 and asthma: We obtained 24 iQTLs (Supplementary Data 4A) associated with this loop (Fig. 2A), all of them being significant nCD4 eQTLs of GSDMB and 21 of them (like the SNPs rs2305479, rs7216389) are nCD4 eQTLs for the asthma risk associated gene ORMDL3 (Supplementary Fig. 5A).