The majority of participating genitourinary pathologists (n = 44; 70%) would ask for familial screening for extrarenal neoplasms such as gastrointestinal stromal tumor in a subset of oncocytic renal neoplasms, particularly SDH-deficient RCC, whereas 19 (30%) would not (Question #25). The gene discussed is SDHB; the disease is gastrointestinal stromal tumor.