Patients with T1D, even with satisfactory glycemic control, present a profile of lipid abnormalities with a detrimental effect on CV risk and a possible potential to promote left ventricular remodeling through increased rates of lipid accumulation in myocardial cells and a surge in insulin resistance and oxidative stress, for instance, triglyceride enrichment of LDL or increased percentage of serum amyloid A in HDL [45]. This evidence concerns the gene INS and type 1 diabetes mellitus.