To understand whether macrophages are influencing CSCs and SOX2 expression, as our in vitro models would suggest, we profiled CD117+, CD133+, and ALDH+ ovarian cancer cells and changes in SOX2 protein expression in the resected tumors from the different treatment groups (Fig. 7A; Supplementary Fig. S6A and S6B). This evidence concerns the gene SOX2 and ovarian carcinoma.