Exposure to cancer cells for 48 hours in vehicle conditions maintained THP1-derived macrophages with traditional marker expression, with 30% M0 cells expressing CD80 and 10% expressing CD206, 60% M1 cells expressing CD80, and 26% M2 cells expressing CD206 (Fig. 1E; Supplementary Fig. S2D). The gene discussed is MRC1; the disease is cancer.