Xianghou Xia et al found that the expression of GSDMD in BC was 1.67 times higher compared with normal tissues and was positively associated with OS and relapse free survival, indicating GSDMD was a promising prognostic marker and could be a predictor of therapeutic response for BC.[32] In our study, we also confirmed the finding that GSDMD was upregulated in BC patients and higher expression of GSDMD was correlated with better OS rates. Here, GSDMD is linked to breast cancer.