The results of quantitative real-time polymerase chain reaction and Western blot data analysis showed that FOS was highly expressed in NASH mice and showed the same trend.[37] GADD45B and GADD45G are members of the growth arrest DNA damage-inducible gene (GADD45) family, respectively, which are involved in cell cycle arrest, DNA repair, apoptosis, innate immunity, and genome stability. The gene discussed is GADD45A; the disease is metabolic dysfunction-associated steatohepatitis.