PF4 and Thrombocytopenia: One hypothesis suggests a phenomenon akin to heparin-induced thrombocytopenia, where platelet activation occurs through antibodies targeting platelet‐factor 4 (anti-PF4)/ heparin associated with thrombosis.[6–8] Generated by platelets, PF4 has the ability to stimulate the development of antibodies that can attach to PF4.