TIMP1 and acute kidney injury: In post-LT for predicting severe AKI, U-OSM was the best overall variable, with a cutoff value of 418 mOsm/l (Figure 2); the child nodes were U-KIM-1 following U-TIMP-1 with an accuracy together above 80%, - (CV 25%) and Cohen’s kappa 0.46 with a moderate agreement, sensitivity 41%, specificity 98.5% and PPV 93% and NPV 78%.