Univariate Cox proportional hazards regression analysis revealed that high PTBP1 expression conferred a greater than two‐fold increase in the risk of mortality, especially cancer‐specific death, in both cohorts (OS: cohort 1, HR = 3.25, 95% CI = 1.48–7.15, p = 0.003; cohort 2, HR = 4.26, 95% CI = 1.73–11.35, p = 0.002; CSS: cohort 1, HR = 2.39, 95% CI = 1.08–5.30, p = 0.031; and cohort 2, HR = 6.35, 95% CI = 1.79–22.60, p = 0.004; Table S2, Supporting Information). Here, PTBP1 is linked to cancer.