IL1B and obesity due to melanocortin 4 receptor deficiency: In last years, the nucleotide‐binding oligomerization domain leucine rich repeat and pyrin domain containing protein 3 (NLRP3) inflammasome multiprotein complex, expressed in immune/inflammatory cells and EGCs, is emerging as critical player in the pathogenesis of inflammatory responses associated with obesity via the processing and release of interleukin (IL)‐1β and IL‐18.15, 16, 17