In GFAP‐positive glial cells no significant differences in the expression levels of NLRP3 inflammasome subunit and pro‐caspase‐1 were observed, while a significant increase in the expression levels of ASC inflammasome subunit and caspase‐1 were detected, as compared with cocultured control EGCs (Figure 6C–G), thus confirming that, in the setting of obesity, activated EGCs were characterized by an hyperactivation of canonical NLRP3/caspase‐1 inflammasome signaling pathway. Here, NLRP3 is linked to Obesity.