Myelin oligodendrocyte glycoprotein antibody (MOG‐IgG)‐associated disease (MOGAD) is a rare and recently defined demyelinating disorder of the central nervous system (CNS), characterized by relapses of optic neuritis (ON), transverse myelitis (TM), and brainstem/brain impairment with a rapidly evolving clinical spectrum [1, 2]. The gene discussed is MOG; the disease is optic neuritis.