Automated quantification confirmed an interstitial expression pattern for Adamts12 with minimal expression in homeostasis as well as early after kidney injury (day 1), but strong upregulation between day 5 and day 10 after UUO surgery, day 14 after IRI, and a slight upregulation at day 7 in adenine-induced kidney injury, all of which are time points that coincide with fibroblast expansion, migration, and fibrogenesis (Supplemental Figure 1, E–J). This evidence concerns the gene ADAMTS12 and kidney injury.