CDH1 and neoplasm: The H376 cells had lost expression of E-cadherin and showed increased expression of Gal-GalNAc, properties typical of a more advanced tumor, whereas the H357 cells from a stage 1 tumor still expressed E-cadherin and were morphologically more similar to the immortalized OKF-6 cells (Fardini et al., 2011; Coppenhagen-Glazer et al., 2015).