FLI1 and Ewing sarcoma: Approximately 85% of cases have a (11:22)(q24;q12) translocation, resulting in an EWS-FLI-1 fusion gene.1 The remaining 15% of cases result in an ES-electroretinographic (ERG) fusion gene.1 ES is a very rare tumor and is typically found in the pelvis, axial skeleton bones, and femur.2 The skeleton is where 80%–85% of ES occur.3 Even more rarely, ES can be found extraskeletally.