Previous research suggests that patients with poorer pathological types, vascular invasion, higher tumor grades, increased Ki67 expression levels, advanced T staging, and N staging are more prone to postoperative recurrence and metastasis, leading to worse prognosis (Shi et al., 2019; Yang et al., 2019; Elimimian et al., 2021; Kim et al., 2020; Tadros et al., 2021). This evidence concerns the gene MKI67 and neoplasm.