Among its most recent contributions, one study elucidated that the application of epigenetic editing technologies to modulate MGMT methylation status, or to regulate its methylation patterns in a rhythmic manner, can significantly impact the chemosensitivity of gliomas to temozolomide (Gonzalez-Aponte et al., 2024; Zapanta et al., 2024). The gene discussed is MGMT; the disease is glioma.