Scholars are currently investigating the pathogenic pathways implicated in the relationship between psoriasis and thyroid diseases, including the overlap of Th1 immune response with IL-23/Th17 axis (35), shared genetic susceptibility loci (Psoriasis susceptibility 1 candidate 1 (PSORS1C1) gene (36), and Tumor necrosis factor α-induced protein 3 (TNFAIP3) gene) (37), the miRNAome of psoriatic skin functionally enriching in thyroid hormone signaling (38), recognition of thyroid antigens by autoantibodies in patients with psoriasis (39), and vitamin D and omega-3 fatty acid deficiencies (40). This evidence concerns the gene PSORS1C1 and hyperinsulinemic hypoglycemia, familial, 4.