RNH1 and coronary artery disorder: Upon stimulation of five interleukins and two glucocorticoids, no matter HDs or CAD patients, some NK cell samples had R-PrI >1, while others had R-PrI <1, and the increase or decrease of each group was inconsistent (Figure 1B), suggesting a heterogeneous response of NK cells to the stimuli in genomic DNA replication.