Extensive researches have demonstrated that interactions between Cxcl10 and its corresponding receptor CXCR3 are pivotal in comprehending various organ-specific autoimmune diseases such as type 1 diabetes, autoimmune thyroiditis, ocular disorders alongside systemic conditions like rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus [[23], [24], [25]]. Here, CXCR3 is linked to systemic lupus erythematosus.