VEGFA and cancer: Apatinib and Vandetanib did not affect the vasculature, while a reduction in blood vessels due to targeting of Vascular Endothelial Growth Factor and other receptors by Linifanib and Cabozantinib [76] Similarly, a microfluidic vascular micro-organs development platform was devised by Phan et al. for effectiveness evaluation of cancer drugs against fighting cancer and inhibiting angiogenesis [77].