PIK3CA and colorectal carcinoma: Table 3 gives an overview of all tested variables, with p-values and crude odds ratios. Within the univariate models, NET presence, lymphovascular invasion and PIK3CA mutation were significant. FIT-IC CRC have a 4-fold increased odds to be a NET tumor (OR= 4.26 [1.46 – 15.40]), a 2-fold increased odds to present with lymphovascular invasion (OR= 2.31 [1.36 – 3.98]) and a 4-fold increased odds to have a PIK3CA mutation compared to SDCRC (OR= 4.25 [1.34 – 16.40]).