FBP1 and non-small cell lung carcinoma: In non-small cell lung cancer cells, OGT overexpression following glutamine deprivation abolishes fructose-1,6-bisphosphatase 1 (FBP1) phosphorylation and enhances β-oxidation gene transcription via FBP1 O-GlcNAcylation, thus promoting cell proliferation [37].