Given the significant damage of atrial cardiomyocytes following doxorubicin treatment, and the fact that partial and complete loss of myosin binding protein H-like causes cardiac conduction defects and dilated cardiomyopathy [192], we considered its upregulation as an adaptive response to alleviate conduction disturbance following doxorubicin treatment. This evidence concerns the gene MYBPHL and dilated cardiomyopathy.