SOX10 and cancer: Our single-cell sequencing analysis further revealed a heterogeneous cellular architecture of the Sox10-KD tumors, characterized by the presence of cycling stem and progenitor cells and a cluster of slow-cycling tumor cells, similar to a type of dormant stem cell that regenerates neural and glial cells after brain injury and in cancer, where quiescent stem cell-like tumor cell populations were associated with tumor initiation and recurrence (Chen et al, 2012; Kalamakis et al, 2019; Llorens-Bobadilla et al, 2015; Xie et al, 2022).