SOX10 and neoplasm: Recently, we identified SOX10 (SRY-Box Transcription Factor 10), which specifies oligodendrocytic lineage differentiation during normal NSC development (Stolt et al, 2002), as a master regulator of the RTK1-subtype of glioblastoma, and demonstrated that SOX10 suppression promotes tumor progression (Wu et al, 2020).