SOX10 and glioblastoma: Following intracranial injection of mGB1 control and mGB1 Sox10 knockdown (Sox10-KD) neurospheres, mGB1 Sox10-KD tumors developed significantly faster than control tumors, showing features consistent with NSC-like glioblastoma, such as invasive growth at the tumor edges and invasion of the contralateral hemisphere (Fig. EV2A,B) (Wang et al, 2020).