LEP and obesity due to melanocortin 4 receptor deficiency: Interestingly, after 8 weeks of EGCG treatment, more significant correlations were observed with obesity parameters such as BW, BMI, waist circumference, hip circumference, % fat, and fat mass, while fewer significant correlations were noted with serum leptin and adiponectin levels, though the direction of these correlations remained consistent with pre-treatment.