MCL can be categorized into three subtypes: conventional (cMCL) with aggressive behaviour, high genomic instability and overexpression of SOX11, the less common leukemic non-nodal (nn)MCL with an indolent behaviour, downregulation of SOX11 [3–5] and lower treatment pressure, and the blastoid variant with high cell proliferation and rapidly progressing clinical course [6]. This evidence concerns the gene SOX11 and mantle cell lymphoma.