GPHN and Anxiety: No amelioration of the Nlgn2 KO anxiety phenotype was observed in male or female Nlgn2 KO/MDGA2 Het mice (Supplementary Fig. 5f-h and Supplementary Table 7), consistent with the lack of an effect of MDGA2 Het on gephyrin aggregation and GABAergic synaptic transmission (Supplementary Fig. 5a–c and Supplementary Table 7).