Elevated expression of programmed cell death protein‐1 (PD1: P = 0.0023) and T‐cell immunoglobulin and mucin‐domain containing‐3 (TIM3: P < 0.0001) in skeletal muscles of patients with IIM were correlated with creatine kinase levels (PD1, r = 0.7072, P < 0.0001; TIM3, r = 0.4808, P = 0.0046). Here, HAVCR2 is linked to acquired idiopathic inflammatory myopathy.