TBK1 and HIV infectious disease: For example, it has been shown that IFI16 can contribute to IFN-I induction through the activation of STING and TBK1 to enhance cGAMP-dependent activation of STING as described in THP-1 cells following HSV-1 and HIV infection, however it is unknown whether the same phenomenon is induced by NiV and MeV [63].