Interestingly, variations in microbiome composition have been noted among different lung cancer types; for example, squamous cell carcinoma patients with TP53 mutations showed a higher abundance of Acidovorax, and the genera Klebsiella, Comamonas, Acidovorax, Polaromonas, and Rhodoferax were more common in small cell carcinoma than in adenocarcinoma (Yu et al., 2016; Dickson et al., 2014; Greathouse et al., 2018). Here, TP53 is linked to adenocarcinoma.