CRY1 and neoplasm: Multiple studies have reported decreasedBMAL1, CRY1-2 and PER1-3, and increasedCLOCK,CSNK1E andTIM in tumor tissue relative to matched healthy mucosa (Honget al., 2014b;Kruglugeret al., 2007;Mazzoccoliet al., 2011,2016;Oshimaet al., 2011;Zenget al., 2014).