BRAF and melanoma: Here we present an interesting case from our department, of a 57-year-old patient, diagnosed in 2019 with stage IV pT4cNx cM1 (lymph nodes metastases) and suspicion of lung metastases, proto-oncogene B-Raf (BRAF) wild-type right hallux malignant melanoma that achieved partial remission initially, afterward complete response with dual ICIs nivolumab (NIVO) and ipilimumab (IPI).