Though this case report and others mentioned above support these statements, further outpatient hematologic testing would be needed in this case to definitely rule out another cause of thrombosis such as protein C and/or S deficiency, antithrombin deficiency, prothrombin mutation, factor V Leiden mutation, or other coagulation disorders. The gene discussed is F2; the disease is hyperinsulinemic hypoglycemia, familial, 4.