SOD2 and infection: Consistent with a central role for oxidative stress responses in cell-intrinsic responses to infection, key antioxidant enzymes (GSR, CAT, GPX1, and PRDX1) were downregulated by YFV-17D (Supplemental Figure 9A) and select genes (SOD2, NFE2L2, and KEAP1) were upregulated by MnTBAP treatment.