CD274 and neoplasm: According to the findings, the expansion of PBLs began on day 3, when the percentage of cell division was 22.4 (±11.9)% in the presence of tumor and increased to 31.2 (±10.8)% when cocultured with anti-PDL1-BiTE/tumor as compared to 3.9 (±3.0)% in PBLs only (P = 0.0002, Figure 6).