As shown in Figures 7(a) and 7(a), CD25 and CD69 increased from 13.2 (±5.6)% and 53.6 (±6.6)% in the condition of PBL/tumor to 19.7 (±2.3)% and 65.4 (±7.8)% in the case of PBL/PDL1-BiTE/tumor, respectively. This evidence concerns the gene CD69 and neoplasm.