Additionally, reductions in hepatic steatosis in WD-fed MMP14LKO mice were not accompanied by protection from diet-induced abnormalities in serum TG, serum cholesterol, serum nonesterified fatty acids, serum low-density lipoprotein cholesterol (LDL-C), serum transaminase elevation, serum albumin (Fig. S4A–F), hepatic cholesterol accumulation, nonesterified fatty acid accumulation (Fig. S5A and B), or changes in hepatic fatty acid oxidation- or de novo lipogenesis-related gene expression in any chow- or diet-induced MMP14LKO group (Fig. S6A–L). The gene discussed is ALB; the disease is fatty liver disease.