The combination of CKAP4, BCL6 and TLR8 for differentiating patients with ICH from HTN controls, CTRLs and IS patients had AUC values of 0.93 (95% CI: 0.89–0.98), 0.95 (95% CI: 0.92–0.99) and 0.82 (95% CI: 0.74–0.89), respectively, with sensitivities of 81.3%, 84.4% and 75%, respectively, and specificities of 100%, 96% and 79.7%, respectively (Figures 7A−C). This evidence concerns the gene CKAP4 and hypertensive disorder.