In this study, we cultured bone-derived chicken dendritic cells (ck-BM-DC) and examined gene expression levels of IFN-α, TLR-3, TLR-7, MHC-I, IL-1β, IL-6, Mx, Casp-3, and Casp-8 pre/post infection with AIV. The gene discussed is CASP3; the disease is infection.