Nikoulina Nikoulina S.E. S.E. Ciaraldi Ciaraldi T.P. T.P. Henry Henry R.R. R.R. Kahn Kahn B.B. B.B. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes J. Clin. The gene discussed is AKT1; the disease is type 2 diabetes mellitus.