In the human multiple myeloma cell line ODA, chromosomal translocation of t(1; 14) (p34; q32) occurs between the switch region of the immunoglobulin heavy chain (IgH) gene (Sμ) of 14q32 and the first intron site of the LAPTM5 gene at 1p34. This evidence concerns the gene LAPTM5 and AL amyloidosis.