PTK2 and mantle cell lymphoma: In another study, the authors demonstrated, through chromatin immunoprecipitation (ChIP) and luciferase assays, how the SRY-related HGM-box transcription factor 11 (SOX11) could bind the PTK2 gene and upregulate FAK expression in MCL cell lines, thus inducing the activation of the AKT and ERK1/2 pathways.