An interesting pharmacological study showed how asiatic acid (AA, a pentacyclic triterpene, used at 40 μM) can interrupt cell cycle progression in the RPMI 8226 MM cell line, decreasing the expression level of FAK and pFAK (hence the activated form), thus highlighting a possible mechanism of action of AA in MM involving FAK (83). The gene discussed is PTK2; the disease is Miyoshi myopathy.