Moreover, many studies showed a clear correlation between high CFL1 expression and aggressive progression of cancer cells [reviewed in Wang et al. (2007), Coumans et al. (2018), Sidani et al. (2007), Xu et al. (2021)], supporting our finding that CFL1 highly significantly correlates with the ability of breast cancer cells to form metastases. The gene discussed is CFL1; the disease is cancer.