CLN2, apart from CLN7, was also found to be a common type in the Russian population.14 CLN1 usually presents under two years of age, with some studies showing late-onset variants and our two patients of CLN1 also presented in early infancy.9 All the patients with mutations in genes including TPP1/CLN2, CLN3, CLN5 and CLN8 presented with a late infantile NCL phenotype in our study population.15 Most of them presented with speech delay, seizures and motor decline along with progressive loss of vision. This evidence concerns the gene MFSD8 and neuronal ceroid lipofuscinosis.