CD3+, CD3-CD19+, and CD16+CD56+ are important indexes for the assessment of the body’s immune function, and Rh-endostatin has a strong modulating effect on immune function, therefore, compared with the single radiotherapy regimen, Rh-endostatin the assessment results of CD3+, CD3-CD19+, CD16+CD56+ index levels in cervical cancer cases were more excellent after combined with simultaneous radiotherapy intervention. This evidence concerns the gene COL18A1 and cervical carcinoma.