LH basal value (OR = 6.92, 95% CI 4.20–11.39), bone age (OR = 1.40, 95% CI 1.24–1.58), and uterine volume (OR = 1.38, 95% CI 1.16–1.65) were identified as predictors of CPP progression in non-obese girls, as shown in Table 4. This evidence concerns the gene PLOD1 and central precocious puberty.